Low Bone Mineral Density with Tenofovir: Does Statistically Significant Mean Clinically Significant?
نویسندگان
چکیده
منابع مشابه
Low bone mineral density with tenofovir: does statistically significant mean clinically significant?
Adults with human immunodeficiency (HIV) infection appear to have a greater prevalence of low bone mineral density (BMD) and of fractures than do adults without HIV infection [1,2]. HIV infection itself may contribute to this greater prevalence. HIV induces inflammation (a known association with accelerated BMD loss), and low BMD has been reported in individuals with untreated HIV infection [1,...
متن کاملGrapefruits and drugs: when is statistically significant clinically significant?
Editorial Lown et al. (1) report a significant advance in describing a new mechanism by which ingested nutrients may change exposure to drug therapy. Grapefruit juice was reported to increase plasma concentrations of felodipine and nifedipine when the drug was concurrently administered with grapefruit juice (2). The potential clinical importance of such an interaction was noted when cyclosporin...
متن کاملStatistically significant sites
Most of us know less about statistics than we feel we should but, even as a scientist, it’s often not necessary to be an expert. When it comes to presenting your data, or reviewing someone else’s, however, it can help to have a ready reference at your fingertips. Before you run out and buy a textbook or ask advice from a colleague, take a look at what the web has to offer. Sites offering online...
متن کاملStatistically Significant Results
Fortunately, the probability that the process was simply a chance encounter can be calculated, and a minimum threshold of statistical significance can be set. If the results are obtained such that the probability that they are simply a chance process is less than this threshold of significance, then we can say the results have a high probability of not being due to chance. Note that the probabi...
متن کاملClassification Using Statistically Significant Rules
Classification based on association rule mining has become a popular technique within the data mining community. However, it has now been emphatically shown that association rules generated solely on the basis of support and confidence are often not statistically significant i.e, the rules generated are artifacts of the particular dataset being mined rather than a relationship inherent in the u...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2010
ISSN: 1058-4838,1537-6591
DOI: 10.1086/656418